2024
Madarasz, Adrian; Xin, Li; Proulx, Steven T
(2024).
Clearance of erythrocytes from the subarachnoid space through cribriform plate lymphatics in female mice.
EBioMedicine, 107(105295), p. 105295.
Elsevier
10.1016/j.ebiom.2024.105295
Sáinz-Jaspeado, Miguel; Proulx, Steven T; Ring, Sarah; Richards, Mark; Martinsson, Pernilla; Li, Xiujuan; Claesson-Welsh, Lena; Ulvmar, Maria H; Jin, Yi
(2024).
VE-cadherin junction dynamics in initial lymphatic vessels promotes lymph node metastasis.
Life science alliance, 7(3)
EMBO Press
10.26508/lsa.202302168
Kelly, Louise; Brown, Christopher; Michalik, Daniel; Hawkes, Cheryl A; Aldea, Roxana; Agarwal, Nivedita; Salib, Rami; Alzetani, Aiman; Ethell, Douglas W; Counts, Scott E; de Leon, Mony; Fossati, Silvia; Koronyo-Hamaoui, Maya; Piazza, Fabrizio; Rich, Steven A; Wolters, Frank J; Snyder, Heather; Ismail, Ozama; Elahi, Fanny; Proulx, Steven T; ...
(2024).
Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA), updates in 2022-2023. Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease: Opportunities for therapy.
Alzheimer's & dementia : the journal of the Alzheimer's Association, 20(2), pp. 1421-1435.
10.1002/alz.13512
2023
Pietilä, Riikka; Del Gaudio, Francesca; He, Liqun; Vázquez-Liébanas, Elisa; Vanlandewijck, Michael; Muhl, Lars; Mocci, Giuseppe; Bjørnholm, Katrine D; Lindblad, Caroline; Fletcher-Sandersjöö, Alexander; Svensson, Mikael; Thelin, Eric P; Liu, Jianping; van Voorden, A Jantine; Torres, Monica; Antila, Salli; Xin, Li; Karlström, Helena; Storm-Mathisen, Jon; Bergersen, Linda Hildegard; ...
(2023).
Molecular anatomy of adult mouse leptomeninges.
Neuron, 111(23), 3745-3764.e7.
Elsevier
10.1016/j.neuron.2023.09.002
Mapunda, Josephine A; Pareja, Javier; Vladymyrov, Mykhailo; Bouillet, Elisa; Hélie, Pauline; Pleskač, Petr; Barcos, Sara; Andrae, Johanna; Vestweber, Dietmar; McDonald, Donald M; Betsholtz, Christer; Deutsch, Urban; Proulx, Steven T; Engelhardt, Britta
(2023).
VE-cadherin in arachnoid and pia mater cells serves as a suitable landmark for in vivo imaging of CNS immune surveillance and inflammation.
Nature communications, 14(1), p. 5837.
Nature Publishing Group
10.1038/s41467-023-41580-4
Spera, Irene; Cousin, Nikola; Ries, Miriam; Kedracka, Anna; Castillo, Alina; Aleandri, Simone; Vladymyrov, Mykhailo; Mapunda, Josephine A; Engelhardt, Britta; Luciani, Paola; Detmar, Michael; Proulx, Steven T
(2023).
Open pathways for cerebrospinal fluid outflow at the cribriform plate along the olfactory nerves.
EBioMedicine, 91(104558), p. 104558.
Elsevier
10.1016/j.ebiom.2023.104558
Proulx, Steven T; Engelhardt, Britta
(2023).
Macrophages clear the way for CNS fluid flow.
The lancet. Neurology, 22(3), pp. 194-195.
Elsevier
10.1016/S1474-4422(23)00028-5
Proulx, Steven T
(2023).
The peri-olfactory pathway: An "e-scent-ial" route for cerebrospinal fluid clearance?
EBioMedicine, 87(104417), p. 104417.
Elsevier
10.1016/j.ebiom.2022.104417
2022
Ineichen, Benjamin V; Okar, Serhat V; Proulx, Steven T; Engelhardt, Britta; Lassmann, Hans; Reich, Daniel S
(2022).
Perivascular spaces and their role in neuroinflammation.
Neuron, 110(21), pp. 3566-3581.
Cell Press
10.1016/j.neuron.2022.10.024
Proulx, Steven T.; Engelhardt, Britta
(2022).
Central nervous system zoning: How brain barriers establish subdivisions for CNS immune privilege and immune surveillance.
Journal of internal medicine, 292(1), pp. 47-67.
Wiley
10.1111/joim.13469
Decker, Yann; Krämer, Jonas; Xin, Li; Müller, Andreas; Scheller, Anja; Fassbender, Klaus; Proulx, Steven T.
(2022).
Magnetic resonance imaging of cerebrospinal fluid outflow after low-rate lateral ventricle infusion in mice.
JCI insight, 7(3)
JCI Insight
10.1172/jci.insight.150881
Friess, Mona C; Kritikos, Ioannis; Schineis, Philipp; Medina-Sanchez, Jessica Danielly; Gkountidi, Anastasia-Olga; Vallone, Angela; Sigmund, Elena C; Schwitter, Corina; Vranova, Martina; Matti, Christoph; Arasa, Jorge; Saygili Demir, Cansaran; Bovay, Esther; Proulx, Steven T; Tomura, Michio; Rot, Antal; Legler, Daniel F; Petrova, Tatiana V; Halin, Cornelia
(2022).
Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics.
Cell reports, 38(5), p. 110334.
Cell Press
10.1016/j.celrep.2022.110334
2021
Polomska, Anna K; Proulx, Steven T.
(2021).
Imaging technology of the lymphatic system.
Advanced drug delivery reviews, 170, pp. 294-311.
Elsevier
10.1016/j.addr.2020.08.013
Weber, Florian; C. Ivan, Daniela; Proulx, Steven T.; Locatelli, Giuseppe; Aleandri, Simone; Luciani, Paola
(2021).
Beyond Trial and Error: A Systematic Development of Liposomes Targeting Primary Macrophages.
Advanced nanoBiomed research, 1(3), p. 2000098.
Wiley
10.1002/anbr.202000098
Proulx, Steven T.
(2021).
Cerebrospinal fluid outflow: a review of the historical and contemporary evidence for arachnoid villi, perineural routes, and dural lymphatics.
Cellular and molecular life sciences : CMLS, 78(6), pp. 2429-2457.
Springer
10.1007/s00018-020-03706-5
2020
Dieterich, Lothar C; Tacconi, Carlotta; Menzi, Franziska; Proulx, Steven T; Kapaklikaya, Kübra; Hamada, Michito; Takahashi, Satoru; Detmar, Michael
(2020).
Lymphatic MAFB regulates vascular patterning during developmental and pathological lymphangiogenesis.
Angiogenesis, 23(3), pp. 411-423.
Springer Netherlands
10.1007/s10456-020-09721-1
Bachmann, Samia B; Proulx, Steven T.; He, Yuliang; Ries, Miriam; Detmar, Michael
(2020).
Differential effects of anaesthesia on the contractility of lymphatic vessels in vivo: authors' reply.
The journal of physiology, 598(10), p. 2037.
The Physiological Society
10.1113/JP279712
2019
Dieterich, Lothar C; Kapaklikaya, Kübra; Cetintas, Timur; Proulx, Steven Thomas; Commerford, Catharina D; Ikenberg, Kristian; Bachmann, Samia B; Scholl, Jeannette; Detmar, Michael
(2019).
Transcriptional profiling of breast cancer-associated lymphatic vessels reveals VCAM-1 as regulator of lymphatic invasion and permeability.
International journal of cancer, 145(10), pp. 2804-2815.
Wiley-Blackwell
10.1002/ijc.32594
Ma, Qiaoli; Decker, Yann; Müller, Andreas; Ineichen, Benjamin V; Proulx, Steven T.
(2019).
Clearance of cerebrospinal fluid from the sacral spine through lymphatic vessels.
Journal of experimental medicine, 216(11), pp. 2492-2502.
Rockefeller University Press
10.1084/jem.20190351
Ma, Qiaoli; Schlegel, Felix; Bachmann, Samia B; Schneider, Hannah; Decker, Yann; Rudin, Markus; Weller, Michael; Proulx, Steven T.; Detmar, Michael
(2019).
Lymphatic outflow of cerebrospinal fluid is reduced in glioma.
Scientific reports, 9(1), p. 14815.
Springer Nature
10.1038/s41598-019-51373-9
Vranova, Martina; Friess, Mona C; Haghayegh Jahromi, Neda; Collado-Diaz, Victor; Vallone, Angela; Hagedorn, Olivia; Jadhav, Maria; Willrodt, Ann-Helen; Polomska, Anna; Leroux, Jean-Christophe; Proulx, Steven Thomas; Halin, Cornelia
(2019).
Opposing roles of endothelial and leukocyte-expressed IL-7Rα in the regulation of psoriasis-like skin inflammation.
Scientific reports, 9(1), p. 11714.
Springer Nature
10.1038/s41598-019-48046-y
Bachmann, Samia B; Gsponer, Denise; Montoya-Zegarra, Javier A; Schneider, Martin; Scholkmann, Felix; Tacconi, Carlotta; Noerrelykke, Simon F; Proulx, Steven T.; Detmar, Michael
(2019).
A Distinct Role of the Autonomic Nervous System in Modulating the Function of Lymphatic Vessels under Physiological and Tumor-Draining Conditions.
Cell reports, 27(11), 3305-3314.e13.
Elsevier
10.1016/j.celrep.2019.05.050
Lenti, Elisa; Bianchessi, Silvia; Proulx, Steven Thomas; Palano, Maria Teresa; Genovese, Luca; Raccosta, Laura; Spinelli, Antonello; Drago, Denise; Andolfo, Annapaola; Alfano, Massimo; Petrova, Tatiana V; Mukenge, Sylvain; Russo, Vincenzo; Brendolan, Andrea
(2019).
Therapeutic Regeneration of Lymphatic and Immune Cell Functions upon Lympho-organoid Transplantation.
Stem cell reports, 12(6), pp. 1260-1268.
Elsevier
10.1016/j.stemcr.2019.04.021
Bachmann, Samia B; Proulx, Steven Thomas; He, Yuliang; Ries, Miriam; Detmar, Michael
(2019).
Differential effects of anaesthesia on the contractility of lymphatic vessels in vivo.
The journal of physiology, 597(11), pp. 2841-2852.
The Physiological Society
10.1113/JP277254
Polomska, Anna K; Proulx, Steven Thomas; Brambilla, Davide; Fehr, Daniel; Bonmarin, Mathias; Brändli, Simon; Meboldt, Mirko; Steuer, Christian; Vasileva, Tsvetina; Reinke, Nils; Leroux, Jean-Christophe; Detmar, Michael
(2019).
Minimally invasive method for the point-of-care quantification of lymphatic vessel function.
JCI insight, 4(4)
JCI Insight
10.1172/jci.insight.126515
Ma, Qiaoli; Ries, Miriam; Decker, Yann; Müller, Andreas; Riner, Chantal; Bücker, Arno; Fassbender, Klaus; Detmar, Michael; Proulx, Steven T.
(2019).
Rapid lymphatic efflux limits cerebrospinal fluid flow to the brain.
Acta neuropathologica, 137(1), pp. 151-165.
Springer-Verlag
10.1007/s00401-018-1916-x
Yoon, Sun-Young; Dieterich, Lothar C; Karaman, Sinem; Proulx, Steven T.; Bachmann, Samia B; Sciaroni, Carol; Detmar, Michael
(2019).
An important role of cutaneous lymphatic vessels in coordinating and promoting anagen hair follicle growth.
PLoS ONE, 14(7), e0220341.
Public Library of Science
10.1371/journal.pone.0220341
2018
Schwager, Simon; Renner, Silvana; Hemmerle, Teresa; Karaman, Sinem; Proulx, Steven T.; Fetz, Roman; Golding-Ochsenbein, Alexandra Michaela; Probst, Philipp; Halin, Cornelia; Neri, Dario; Detmar, Michael
(2018).
Antibody-mediated delivery of VEGF-C potently reduces chronic skin inflammation.
JCI insight, 3(23)
JCI Insight
10.1172/jci.insight.124850
Ma, Qiaoli; Dieterich, Lothar C; Ikenberg, Kristian; Bachmann, Samia B; Mangana, Johanna; Proulx, Steven T.; Amann, Valerie C; Levesque, Mitchell P; Dummer, Reinhard; Baluk, Peter; McDonald, Donald M; Detmar, Michael
(2018).
Unexpected contribution of lymphatic vessels to promotion of distant metastatic tumor spread.
Science Advances, 4(8), eaat4758.
American Association for the Advancement of Science
10.1126/sciadv.aat4758
Bachmann, Samia B; Detmar, Michael; Proulx, Steven T.
(2018).
Visualization and Measurement of Lymphatic Function In Vivo.
Methods in molecular biology, 1846, pp. 197-211.
Springer
10.1007/978-1-4939-8712-2_13
2017
Ma, Qiaoli; Ineichen, Benjamin V; Detmar, Michael; Proulx, Steven T.
(2017).
Outflow of cerebrospinal fluid is predominantly through lymphatic vessels and is reduced in aged mice.
Nature communications, 8(1), p. 1434.
Springer Nature
10.1038/s41467-017-01484-6
Gousopoulos, Epameinondas; Proulx, Steven T; Bachmann, Samia B; Dieterich, Lothar C; Scholl, Jeannette; Karaman, Sinem; Bianchi, Roberta; Detmar, Michael
(2017).
An Important Role of VEGF-C in Promoting Lymphedema Development.
Journal of investigative dermatology, 137(9), pp. 1995-2004.
Elsevier
10.1016/j.jid.2017.04.033
Teijeira, Alvaro; Hunter, Morgan C; Russo, Erica; Proulx, Steven T; Frei, Thomas; Debes, Gudrun F; Coles, Marc; Melero, Ignacio; Detmar, Michael; Rouzaut, Ana; Halin, Cornelia
(2017).
T Cell Migration from Inflamed Skin to Draining Lymph Nodes Requires Intralymphatic Crawling Supported by ICAM-1/LFA-1 Interactions.
Cell reports, 18(4), pp. 857-865.
Cell Press
10.1016/j.celrep.2016.12.078
Proulx, Steven T; Ma, Qiaoli; Andina, Diana; Leroux, Jean-Christophe; Detmar, Michael
(2017).
Quantitative measurement of lymphatic function in mice by noninvasive near-infrared imaging of a peripheral vein.
JCI insight, 2(1), pp. 1-13.
JCI Insight
10.1172/jci.insight.90861
Cui, Jihong; Hollmén, Maija; Li, Lina; Chen, Yong; Proulx, Steven T; Reker, Daniel; Schneider, Gisbert; Detmar, Michael
(2017).
New use of an old drug: inhibition of breast cancer stem cells by benztropine mesylate.
OncoTarget, 8(1), pp. 1007-1022.
Impact Journals LLC
10.18632/oncotarget.13537
Bianchi, Roberta; Russo, Erica; Bachmann, Samia B; Proulx, Steven T; Sesartic, Marko; Smaadahl, Nora; Watson, Steve P; Buckley, Christopher D; Halin, Cornelia; Detmar, Michael
(2017).
Postnatal Deletion of Podoplanin in Lymphatic Endothelium Results in Blood Filling of the Lymphatic System and Impairs Dendritic Cell Migration to Lymph Nodes.
Arteriosclerosis, thrombosis, and vascular biology, 37(1), pp. 108-117.
American Heart Association
10.1161/ATVBAHA.116.308020
Gousopoulos, Epameinondas; Karaman, Sinem; Proulx, Steven T; Leu, Kristin; Buschle, Dorina; Detmar, Michael
(2017).
High-Fat Diet in the Absence of Obesity Does Not Aggravate Surgically Induced Lymphoedema in Mice.
European surgical research, 58(3-4), pp. 180-192.
Karger
10.1159/000461579
2016
Gousopoulos, Epameinondas; Proulx, Steven T; Bachmann, Samia B; Scholl, Jeannette; Dionyssiou, Dimitris; Demiri, Efterpi; Halin, Cornelia; Dieterich, Lothar C; Detmar, Michael
(2016).
Regulatory T cell transfer ameliorates lymphedema and promotes lymphatic vessel function.
JCI insight, 1(16), pp. 1-15.
JCI Insight
10.1172/jci.insight.89081
Ochsenbein, Alexandra M; Karaman, Sinem; Proulx, Steven T; Goldmann, Rhea; Chittazhathu, Jyothi; Dasargyri, Athanasia; Chong, Chloé; Leroux, Jean-Christophe; Stanley, E Richard; Detmar, Michael
(2016).
Regulation of lymphangiogenesis in the diaphragm by macrophages and VEGFR-3 signaling.
Angiogenesis, 19(4), pp. 513-524.
Springer Netherlands
10.1007/s10456-016-9523-8
Gousopoulos, Epameinondas; Proulx, Steven T; Scholl, Jeannette; Uecker, Maja; Detmar, Michael
(2016).
Prominent Lymphatic Vessel Hyperplasia with Progressive Dysfunction and Distinct Immune Cell Infiltration in Lymphedema.
American journal of pathology, 186(8), pp. 2193-2203.
Elsevier
10.1016/j.ajpath.2016.04.006
Christiansen, Ailsa J; Dieterich, Lothar C; Ohs, Isabel; Bachmann, Samia B; Bianchi, Roberta; Proulx, Steven T; Hollmén, Maija; Aebischer, David; Detmar, Michael
(2016).
Lymphatic endothelial cells attenuate inflammation via suppression of dendritic cell maturation.
OncoTarget, 7(26), pp. 39421-39435.
Impact Journals LLC
10.18632/oncotarget.9820
Chong, Chloé; Scholkmann, Felix; Bachmann, Samia B; Luciani, Paola; Leroux, Jean-Christophe; Detmar, Michael; Proulx, Steven T
(2016).
In vivo visualization and quantification of collecting lymphatic vessel contractility using near-infrared imaging.
Scientific Reports, 6, p. 22930.
Nature Publishing Group
10.1038/srep22930
Dasargyri, Athanasia; Hervella, Pablo; Christiansen, Ailsa; Proulx, Steven T; Detmar, Michael; Leroux, Jean-Christophe
(2016).
Findings questioning the involvement of Sigma-1 receptor in the uptake of anisamide-decorated particles.
Journal of controlled release, 224, pp. 229-238.
Elsevier
10.1016/j.jconrel.2016.01.021
Brambilla, Davide; Proulx, Steven T; Marschalkova, Patrizia; Detmar, Michael; Leroux, Jean-Christophe
(2016).
Microneedles for the Noninvasive Structural and Functional Assessment of Dermal Lymphatic Vessels.
Small, 12(8), pp. 1053-1061.
Wiley-VCH
10.1002/smll.201503093
Ochsenbein, Alexandra M; Karaman, Sinem; Proulx, Steven T; Berchtold, Michaela; Jurisic, Giorgia; Stoeckli, Esther T; Detmar, Michael
(2016).
Endothelial cell-derived semaphorin 3A inhibits filopodia formation by blood vascular tip cells.
Development, 143(4), pp. 589-594.
Company of Biologists Limited
10.1242/dev.127670
Escobedo, Noelia; Proulx, Steven T; Karaman, Sinem; Dillard, Miriam E; Johnson, Nicole; Detmar, Michael; Oliver, Guillermo
(2016).
Restoration of lymphatic function rescues obesity in Prox1-haploinsufficient mice.
JCI insight, 1(2), pp. 1-17.
JCI Insight
10.1172/jci.insight.85096
2015
Karaman, Sinem; Buschle, Dorina; Luciani, Paola; Leroux, Jean-Christophe; Detmar, Michael; Proulx, Steven T
(2015).
Decline of lymphatic vessel density and function in murine skin during aging.
Angiogenesis, 18(4), pp. 489-498.
Springer Netherlands
10.1007/s10456-015-9479-0
Aspelund, Aleksanteri; Antila, Salli; Proulx, Steven T; Karlsen, Tine Veronica; Karaman, Sinem; Detmar, Michael; Wiig, Helge; Alitalo, Kari
(2015).
A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules.
The Journal of experimental medicine, 212(7), pp. 991-999.
Rockefeller Univ. Press
10.1084/jem.20142290
Li, Xue; Martinez-Lozano Sinues, Pablo; Dallmann, Robert; Bregy, Lukas; Hollmén, Maija; Proulx, Steven; Brown, Steven A; Detmar, Michael; Kohler, Malcolm; Zenobi, Renato
(2015).
Drug Pharmacokinetics Determined by Real-Time Analysis of Mouse Breath.
Angewandte Chemie (International ed.), 54(27), pp. 7815-7818.
Wiley-VCH
10.1002/anie.201503312
Moalli, Federica; Proulx, Steven T; Schwendener, Reto; Detmar, Michael; Schlapbach, Christoph; Stein, Jens Volker
(2015).
Intravital and whole-organ imaging reveals capture of melanoma-derived antigen by lymph node subcapsular macrophages leading to widespread deposition on follicular dendritic cells.
Frontiers in immunology, 6(114), p. 114.
Frontiers Research Foundation
10.3389/fimmu.2015.00114
Bianchi, Roberta; Teijeira, Alvaro; Proulx, Steven T; Christiansen, Ailsa J; Seidel, Catharina D; Rülicke, Thomas; Mäkinen, Taija; Hägerling, René; Halin, Cornelia; Detmar, Michael
(2015).
A transgenic Prox1-Cre-tdTomato reporter mouse for lymphatic vessel research.
PLoS ONE, 10(4), e0122976.
Public Library of Science
10.1371/journal.pone.0122976
2014
Weber, Benedikt; Robert, Jérôme; Ksiazek, Agnieszka; Wyss, Yves; Frese, Laura; Slamecka, Jaroslav; Kehl, Debora; Modregger, Peter; Peter, Silvia; Stampanoni, Marco; Proulx, Steven; Falk, Volkmar; Hoerstrup, Simon P
(2014).
Living-engineered valves for transcatheter venous valve repair.
Tissue engineering. Part C, Methods, 20(6), pp. 451-463.
Mary Ann Liebert
10.1089/ten.TEC.2013.0187
Blum, Katrin S; Karaman, Sinem; Proulx, Steven T; Ochsenbein, Alexandra M; Luciani, Paola; Leroux, Jean-Christophe; Wolfrum, Christian; Detmar, Michael
(2014).
Chronic high-fat diet impairs collecting lymphatic vessel function in mice.
PLoS ONE, 9(4), e94713.
Public Library of Science
10.1371/journal.pone.0094713
2013
Proulx, Steven T; Luciani, Paola; Dieterich, Lothar C; Karaman, Sinem; Leroux, Jean-Christophe; Detmar, Michael
(2013).
Expansion of the lymphatic vasculature in cancer and inflammation: new opportunities for in vivo imaging and drug delivery.
Journal of controlled release, 172(2), pp. 550-557.
Elsevier
10.1016/j.jconrel.2013.04.027
Iolyeva, Maria; Aebischer, David; Proulx, Steven T; Willrodt, Ann-Helen; Ecoiffier, Tatiana; Häner, Simone; Bouchaud, Grégory; Krieg, Carsten; Onder, Lucas; Ludewig, Burkhard; Santambrogio, Laura; Boyman, Onur; Chen, Lu; Finke, Daniela; Halin, Cornelia
(2013).
Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage.
Blood, 122(13), pp. 2271-2281.
American Society of Hematology
10.1182/blood-2013-01-478073
Weber, Benedikt; Kehl, Debora; Bleul, Ulrich; Behr, Luc; Sammut, Sébastien; Frese, Laura; Ksiazek, Agnieszka; Achermann, Josef; Stranzinger, Gerald; Robert, Jérôme; Sanders, Bart; Sidler, Michele; Brokopp, Chad E.; Proulx, Steven T.; Frauenfelder, Thomas; Schoenauer, Roman; Emmert, Maximilian Y.; Falk, Volkmar; Hoerstrup, Simon P.
(2013).
In vitro fabrication of autologous living tissue-engineered vascular grafts based on prenatally harvested ovine amniotic fluid-derived stem cells.
Journal of tissue engineering and regenerative medicine, 10(1), pp. 52-70.
John Wiley & Sons
10.1002/term.1781
Alitalo, Annamari K; Proulx, Steven T; Karaman, Sinem; Aebischer, David; Martino, Stefania; Jost, Manuela; Schneider, Nicole; Bry, Maija; Detmar, Michael
(2013).
VEGF-C and VEGF-D blockade inhibits inflammatory skin carcinogenesis.
Cancer research, 73(14), pp. 4212-4221.
American Association for Cancer Research AACR
10.1158/0008-5472.CAN-12-4539
Proulx, Steven T; Detmar, Michael
(2013).
Molecular mechanisms and imaging of lymphatic metastasis.
Experimental cell research, 319(11), pp. 1611-1617.
Elsevier
10.1016/j.yexcr.2013.03.009
Proulx, Steven T; Luciani, Paola; Christiansen, Ailsa; Karaman, Sinem; Blum, Katrin S; Rinderknecht, Matthias; Leroux, Jean-Christophe; Detmar, Michael
(2013).
Use of a PEG-conjugated bright near-infrared dye for functional imaging of rerouting of tumor lymphatic drainage after sentinel lymph node metastasis.
Biomaterials, 34(21), pp. 5128-5137.
Elsevier
10.1016/j.biomaterials.2013.03.034
Proulx, Steven T; Luciani, Paola; Alitalo, Annamari; Mumprecht, Viviane; Christiansen, Ailsa J; Huggenberger, Reto; Leroux, Jean-Christophe; Detmar, Michael
(2013).
Non-invasive dynamic near-infrared imaging and quantification of vascular leakage in vivo.
Angiogenesis, 16(3), pp. 525-540.
Springer Netherlands
10.1007/s10456-013-9332-2
Blum, Katrin S; Proulx, Steven T; Luciani, Paola; Leroux, Jean-Christophe; Detmar, Michael
(2013).
Dynamics of lymphatic regeneration and flow patterns after lymph node dissection.
Breast cancer research and treatment, 139(1), pp. 81-86.
Springer
10.1007/s10549-013-2537-7
2012
Duong, Tam; Proulx, Steven T; Luciani, Paola; Leroux, Jean-Christophe; Detmar, Michael; Koopman, Peter; Francois, Mathias
(2012).
Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice.
Cancer research, 72(12), pp. 3105-3114.
American Association for Cancer Research AACR
10.1158/0008-5472.CAN-11-4026
Proulx, Steven T; Detmar, Michael
(2012).
Watching lymphatic vessels grow by making them glow.
Cell research, 22(1), pp. 12-13.
Nature Publishing Group
10.1038/cr.2011.191
2010
Mumprecht, Viviane; Honer, Michael; Vigl, Benjamin; Proulx, Steven T; Trachsel, Eveline; Kaspar, Manuela; Banziger-Tobler, Nadja E; Schibli, Roger; Neri, Dario; Detmar, Michael
(2010).
In vivo imaging of inflammation- and tumor-induced lymph node lymphangiogenesis by immuno-positron emission tomography.
Cancer research, 70(21), pp. 8842-8851.
American Association for Cancer Research AACR
10.1158/0008-5472.CAN-10-0896
Jurisic, Giorgia; Iolyeva, Maria; Proulx, Steven T; Halin, Cornelia; Detmar, Michael
(2010).
Thymus cell antigen 1 (Thy1, CD90) is expressed by lymphatic vessels and mediates cell adhesion to lymphatic endothelium.
Experimental cell research, 316(17), pp. 2982-2992.
Elsevier
10.1016/j.yexcr.2010.06.013
Huggenberger, Reto; Ullmann, Stefan; Proulx, Steven T; Pytowski, Bronislaw; Alitalo, Kari; Detmar, Michael
(2010).
Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation.
The Journal of experimental medicine, 207(10), pp. 2255-2269.
Rockefeller Univ. Press
10.1084/jem.20100559
Proulx, Steven T; Luciani, Paola; Derzsi, Stefanie; Rinderknecht, Matthias; Mumprecht, Viviane; Leroux, Jean-Christophe; Detmar, Michael
(2010).
Quantitative imaging of lymphatic function with liposomal indocyanine green.
Cancer research, 70(18), pp. 7053-7062.
American Association for Cancer Research AACR
10.1158/0008-5472.CAN-10-0271
Papuga, M Owen; Proulx, Steven T; Kwok, Edmund; You, Zhigang; Rubery, Paul T; Dougherty, Paul E; Hilton, Matthew J; Awad, Hani A; Schwarz, Edward M
(2010).
Chronic axial compression of the mouse tail segment induces MRI bone marrow edema changes that correlate with increased marrow vasculature and cellularity.
Journal of orthopaedic research, 28(9), pp. 1220-1228.
Wiley
10.1002/jor.21103
Li, Jie; Kuzin, Igor; Moshkani, Safiehkhatoon; Proulx, Steven T; Xing, Lianping; Skrombolas, Denise; Dunn, Robert; Sanz, Iñaki; Schwarz, Edward M; Bottaro, Andrea
(2010).
Expanded CD23(+)/CD21(hi) B cells in inflamed lymph nodes are associated with the onset of inflammatory-erosive arthritis in TNF-transgenic mice and are targets of anti-CD20 therapy.
Journal of immunology, 184(11), pp. 6142-6150.
American Association of Immunologists
10.4049/jimmunol.0903489
Li, Dan; Gromov, Kirill; Proulx, Steven T; Xie, Chao; Li, Jie; Crane, Daniel P; Søballe, Kjeld; O'Keefe, Regis J; Awad, Hani A; Xing, Lianping; Schwarz, Edward M
(2010).
Effects of antiresorptive agents on osteomyelitis: novel insights into the pathogenesis of osteonecrosis of the jaw.
Annals of the New York Academy of Sciences, 1192(1), pp. 84-94.
Wiley
10.1111/j.1749-6632.2009.05210.x
Schwarz, Edward M; Proulx, Steven T; Ritchlin, Christopher T; Boyce, Brendan F; Xing, Lianping
(2010).
The role of bone marrow edema and lymphangiogenesis in inflammatory-erosive arthritis.
Advances in experimental medicine and biology, 658, pp. 1-10.
Springer
10.1007/978-1-4419-1050-9_1
2009
Guo, Ruolin; Zhou, Quan; Proulx, Steven T; Wood, Ronald; Ji, Rui-Cheng; Ritchlin, Christopher T; Pytowski, Bronislaw; Zhu, Zhenping; Wang, Yong-Jun; Schwarz, Edward M; Xing, Lianping
(2009).
Inhibition of lymphangiogenesis and lymphatic drainage via vascular endothelial growth factor receptor 3 blockade increases the severity of inflammation in a mouse model of chronic inflammatory arthritis.
Arthritis & rheumatism, 60(9), pp. 2666-2676.
Wiley-Blackwell
10.1002/art.24764
Ritchlin, Christopher T; Proulx, Steven T; Schwarz, Edward S
(2009).
Translational perspectives on psoriatic arthritis.
The journal of rheumatology. Supplement, 83, pp. 30-34.
The Journal of Rheumatology Publishing Company Limited
10.3899/jrheum.090219
2008
Tsutsumi, Ryosuke; Hock, Colleen; Bechtold, C Dustin; Proulx, Steven T; Bukata, Susan V; Ito, Hiromu; Awad, Hani A; Nakamura, Takashi; O'Keefe, Regis J; Schwarz, Edward M
(2008).
Differential effects of biologic versus bisphosphonate inhibition of wear debris-induced osteolysis assessed by longitudinal micro-CT.
Journal of orthopaedic research, 26(10), pp. 1340-1346.
Wiley
10.1002/jor.20620
Proulx, Steven T; Kwok, Edmund; You, Zhigang; Papuga, M Owen; Beck, Christopher A; Shealy, David J; Calvi, Laura M; Ritchlin, Christopher T; Awad, Hani A; Boyce, Brendan F; Xing, Lianping; Schwarz, Edward M
(2008).
Elucidating bone marrow edema and myelopoiesis in murine arthritis using contrast-enhanced magnetic resonance imaging.
Arthritis & rheumatism, 58(7), pp. 2019-2029.
Wiley-Blackwell
10.1002/art.23546
2007
Proulx, Steven T; Kwok, Edmund; You, Zhigang; Papuga, M Owen; Beck, Christopher A; Shealy, David J; Ritchlin, Christopher T; Awad, Hani A; Boyce, Brendan F; Xing, Lianping; Schwarz, Edward M
(2007).
Longitudinal assessment of synovial, lymph node, and bone volumes in inflammatory arthritis in mice by in vivo magnetic resonance imaging and microfocal computed tomography.
Arthritis & rheumatism, 56(12), pp. 4024-4037.
Wiley-Blackwell
10.1002/art.23128
Proulx, Steven T; Kwok, Edmund; You, Zhigang; Beck, Christopher A; Shealy, David J; Ritchlin, Christopher T; Boyce, Brendan F; Xing, Lianping; Schwarz, Edward M
(2007).
MRI and quantification of draining lymph node function in inflammatory arthritis.
Annals of the New York Academy of Sciences, 1117(1), pp. 106-123.
Wiley
10.1196/annals.1402.016
Zhang, Qian; Lu, Yan; Proulx, Steven T; Guo, Ruolin; Yao, Zhenqiang; Schwarz, Edward M; Boyce, Brendan F; Xing, Lianping
(2007).
Increased lymphangiogenesis in joints of mice with inflammatory arthritis.
Arthritis research & therapy, 9(6), R118.
BioMed Central
10.1186/ar2326
